Sensory Processing in Children and Adolescents with Neurofibromatosis Type 1

Despite the evidence of elevated autistic behaviors and co-occurring neurodevelopmental difficulties in many children with neurofibromatosis type 1 (NF1), we have a limited understanding sensory processing challenges that may occur condition. This study examined profile adolescents NF1 investigated relationships between profiles patient characteristics neuropsychological functioning. The parent/caregivers 152 96 typically developing completed Sensory Profile 2 (SP2), along standardized questionnaires assessing behaviors, ADHD symptoms, internalizing adaptive functioning, social skills. Intellectual functioning was also assessed. SP2 data indicated problems compared to children. Over 40% displayed differences registration (missing input) were unusually sensitive avoidant stimuli. Sixty percent one or more modalities. Elevated symptoms associated severe difficulties. first detailed assessment processing, alongside other clinical features, relatively large cohort demonstrates skills behavior, as well psychological well-being. Our characterization within genetic syndrome help facilitate targeted interventions support overall